Top 15 Pharmaceutical Companies in the United States

When it comes to selecting the world’s largest pharmaceutical businesses, one company’s position might fluctuate from year to year. This is especially true when a company’s market capitalization, also known as market cap value, is used to determine its status.

The most significant reason for this is the hundreds of mergers and acquisitions that occur on a regular basis. This has a significant impact on market capitalization and should be taken into account when rating the best companies.

15 Pharmaceutical Companies in the United States, Ranked by Their Market Capitalization

According to data from research company GlobalData, below is a breakdown of the top 15 pharma firms by revenue in 2019. We looked into the best performances and compiled a ranked list of the top 15 pharmaceutical firms in the US, starting with the 15th and working our way up to the first, based on their market capitalization.

 15. Alexion Pharmaceuticals Inc. – $29.37 Billion Dollars

As of July 2019, Alexion Pharmaceuticals Inc is the fifteenth biggest pharmaceutical firm in the United States. It is ranked as the 467th biggest in the world.   Alexion is based in Connecticut, United States of America, and is listed on the NASDAQ Stock Exchange. They make and sell pharmaceutical and healthcare items.

  • HeadQuarters: Boston, Massachusetts, United States
  • For general inquiries, please contact our Global Headquarters at 1-475-230-2596.

14.  Regeneron Pharmaceuticals Inc. –  $34.32 Billion Dollars

As of July 2019, the fourteenth-largest pharmaceutical firm in the United States was rated 400th in the world. It was once the 263rd largest in the world, but owing to a declining market cap, it was downgraded. The NASDAQ Stock Exchange lists this corporation, which is headquartered in the United States. They work in the healthcare and pharmaceutical industries, doing research, development, and manufacturing.

13. Baxter International Inc. –  $41.78 Billion Dollars

As of July 2019, Baxter International Inc was the thirteenth-largest pharmaceutical corporation in the US. It is also ranked 301st biggest on Earth. The New York Stock Exchange has this corporation listed. Baxter International Inc is dedicated to the development of medical technologies and healthcare solutions for the treatment of immune disorders and renal disease. They are based in the United States of America.

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12. Vertex Pharmaceuticals Inc – $46.97 Billion Dollars

By market value, Vertex Pharmaceuticals Incorporated is the twelfth-largest pharmaceutical company in the United States for 2019. In the world ranking, the firm is ranked 259th. Vertex is based in the United States and is traded on the New York Stock Exchange (NASDAQ). It is a biotechnology, biopharmaceutical, and healthcare firm that specializes in the research and manufacturing of medications and healthcare products.

11. Zoetis Inc. – $54.32 Billion Dollars

Zoetis Inc is a pharmaceutical firm situated in the United States of America, with a market capitalization of $11 billion and a global ranking of 212. It makes medication and immunizations for animals and is traded on the New York Stock Exchange.

  • HeadQuarters:  Parsippany-Troy Hills, New Jersey, United States
  • In the U.S., call 1-888-Zoetis 1 (1-888-963-8471).

10. Shire PLC – $57.62 Billion Dollars

Shire PLC is the tenth-largest pharmaceutical business established in the United Kingdom, and it is rated number one in the world, having dropped from number 187 in March 2019 to number one in July of the same year. This corporation is based in the United States and is listed on the London Stock Exchange. This biopharmaceutical firm produces biopharmaceuticals, healthcare items, and medications.

  • HeadQuarters: Massachusetts, United States

9. Celgene Corporation – $65.19 Billion Dollars

Celgene Corporation has risen from its prior market valuation of $44.8 billion in March 2019 to become the ninth-largest pharmaceutical business in the United States as of July 2019. It is ranked as the166th biggest in the world, up to two places from March 2019.

Celgene Corporation is a pharmaceutical company based in the United States that is traded on the NASDAQ Stock Exchange. It is a multinational biopharmaceutical firm focused on the research, development, and commercialization of healthcare and pharmaceutical products for the treatment of severe immunological, inflammatory, and malignant diseases.

  • HeadQuarters: Summit, New Jersey, United States
  • Contact Info: 1-800-332-2056 (toll free U.S. only)

8. Bristol-Myers Squibb – $74.18 Billion Dollars

With a market valuation of $74.18 billion, Bristol-Myers Squibb is the eighth largest pharmaceutical firm in the United States, down just over $10 billion from December 2018 to July 2019. BMS is positioned 139th in the world as of July 2019, down from its prior position of 121 held since March of this year.

The corporation is based in the United States and trades on the New York Stock Exchange. The corporation has a workforce of 23,700 people. It is a multinational biopharmaceutical firm specializing in the research, development, and distribution of medications to treat critical diseases.

  • HeadQuarters:  NewYork, United States 
  • Contact Info: 1-800-321-1335 (toll free U.S. only)

7. AbbVie Inc. – $107.51 Billion Dollars

Between December 2018 and July 2019, AbbVie Inc’s market capitalization plummeted from $139.6 billion to $107.51 billion. By market capitalization, it is the seventh-largest pharmaceutical firm in the United States and the 89th largest globally.

The New York Stock Exchange lists this corporation, which is headquartered in the United States. It’s a multinational corporation with 29,000 employees that works with scientists, researchers, and communicators to create and discover pharmaceutical and healthcare products. They also produce and sell these items all over the world.

  • HeadQuarters: Lake Bluff, Illinois, United States
  • Contact Info: If you have a question that isn’t answered, please call at 1-800-222-6885.

6. Eli Lilly and Company – $107.56 Billion Dollars

As of July 1, 2019, Eli Lilly and Corporation is the sixth-biggest pharmaceutical company in the United States and the 88th largest in the world. The New York Stock Exchange is where it is listed. Eli Lilly is a pharmaceutical and healthcare product firm that focuses on studying and manufacturing biomedicines, medications for cancer and diabetes in humans, as well as animal pharmaceuticals and healthcare products.

The firm employs 41,000 people. The corporation had a market capitalization of $122.6 billion in December of 2018, however, it has declined from then till July of 2019.

  • HeadQuarters: Indianapolis, Indiana, United States
  • Contact Info:  For more information contact The Lilly Answers Center at 1-800-Lilly-Rx (1-800-545-5979)

5. Amgen Inc. – $124 Billion Dollars

Amgen is the fifth-largest pharmaceutical corporation in the United States. The market capitalization was $124.40 billion in December of 2018. Between this period until July of 2019, the firm lost $12 billion in its MC. It is now the world’s 82nd largest pharmaceutical firm. Amgen is a pharmaceutical company based in the United States that is traded on the NASDAQ stock exchange.

The firm is a biotech industry leader, specializing in biotech product research, development, and manufacturing. It has a workforce of over 2,000 people. Amgen’s main areas of concentration are battling heart disease, cancer, and infection prevention, as well as efforts to improve patient-provider communication. Amgen has a workforce of 20,000 people.

  • HeadQuarters: Thousand Oaks, California, United States
  • Contact Info: Corporate Headquarters One Amgen Center DriveThousand Oaks, CA 91320-1799 +1 805-447-1000

4. Abbott Laboratories –  $148.37 Billion Dollars

In December of 2018, Abbott Laboratories had a market capitalization of $127 billion. Between December 2018 and July 1, 2019, the company’s market cap increased to $148.37 billion. It is the world’s 58th largest pharmaceutical firm and the fourth largest in the United States. Between March and July of this year, it moved up one position in the world rankings.

Abbott Laboratories is a multinational firm with a presence in over 150 countries across the world and employs over 99,000 people. It is listed on the New York Stock Exchange and is based in the United States. Their primary duties include diabetes diagnosis, diet, neuromodulation, and medicines.

  • HeadQuarters: Chicago, Illinois, United States
  • Contact Info:  Phone: 1-877-4Abbott
  • Email: add.ecommerce@abbott.com

3. Merck & Co. – $215.88 Billion Dollars

Merck & Co. is the third-biggest pharmaceutical firm in the United States and the world’s 33rd largest. On December 31, 2018, the company’s market capitalization was $198.7 billion, however, it has subsequently increased to $215.88 billion as of July 1, 2019.

It is a healthcare and pharmaceutical development and manufacturing firm that is listed on the New York Stock Exchange. This is a firm established in the United States that provides medications and vaccinations for humans as well as animal health products on a global scale. Merck & Co. has a global workforce of 69,000 employees.

  • HeadQuarters: Kenilworth, New Jersey, United States
  • Contact Info: 1-800-444-2080

2. Pfizer – $240.86 Billion Dollars

Pfizer Inc had a market capitalization of $240.86 billion in July of this year, down from 253.2 billion on December 31, 2018. As of July 2019, it is the second-largest pharmaceutical corporation in the United States, and it is rated 23rd globally.

The New York Stock Exchange is where the corporation is listed. New York is the company’s headquarters. It produces pharmaceuticals and other items and manages over 500,000 lab tests. Pfizer is also participating in over 36 clinical studies that are undertaken prior to the prescription of drugs and therapies. The firm creates medications for a variety of disorders, ranging from the basic to the complex. They have a team of 1,500 scientists. ​​​​​​​

  • HeadQuarters: New York, United States. 
  • Contact Info: Customer Service and Product Inquiries: 1-800-TRY-FIRST (1-800-879-3477) Monday through Friday 9:00 a.m. to 7:00 p.m. EST
  • Corporate Office: (212) 733-2323  235 East 42nd Street New York, NY 10017

1. Johnson & Johnson – $369.80 Billion Dollars

As of July 1, 2019, Johnson & Johnson is the top-ranked pharmaceutical firm in the United States. As of July 2019, it is ranked number 10 in the world, down one spot from March of the same year. The New York Stock Exchange has this corporation listed.

The corporation is headquartered in the United States and produces consumer items, medical equipment and gadgets, and pharmaceutical products. The firm employs 125, 000 people and works in 60 different nations throughout the world.

  • HeadQuarters: New Brunswick, New Jersey, United States. 

Contact Info: Main Office: One Johnson & Johnson Plaza New Brunswick, New Jersey 08933 (732) 524-0400